Shifting Paradigm in Early Detection and Prediction of Alzheimer's Disease

1. Overview

Disease prevalence and global disease burden have shifted the attention towards neurodegenerative disorders like dementia in late life. In this chapter, we will focus on neurocognitive disorders among the elderly. We begin by reviewing evidence-based prevalence studies, presenting cases, signs and symptoms, early detection and prediction, challenges faced by the elderly, comorbidities, caregiver burden, and assessment followed by possible management. The 21^st century is full of enthusiasm, recent advancements, emerging technologies, pandemics, and drastic changes in climate and lifestyles, that eventually put us human beings at ease with disease. In the era of digitization, rapid growth, and drastic changes make every individual move even faster than usual. Nearly every day, millions of people of growing age apart from the adult population are getting engaged in various surgical procedures. Most people, from ordinary individuals to celebrities are spending billions of dollars per year on numerous cosmetic and plastic surgeries to reduce signs of aging and unexpectedly the number is getting higher day by day but what are the crucial steps that one is taking in managing their age-related cognitive change or adverse change in cognitive functions. In this sensational era, people are motivated and desire to undergo plastic surgery to look younger than their age. Still, the fact is that specific changes are bound to happen as we age. People are unable to manage any cognitive decline with age so here in that case what are the possible steps that one can take to manage their cognitive ability as early as possible? People are striving towards perfection in physiological and mental capacity but unfortunately, as we age, physiological changes are inevitable, and there may be emotional and cognitive changes as well.