A Bio-Therapeutically Squalene: Case Review for T&CM Students as a Wound-Healing Compound

Abstract

Although the skin tissue on our bodies is a well-organized structure with high biomechanical properties like tensile strength and friction, we have all experienced various types of wounds throughout our lives owing to numerous etiological factors. In the general population, it is a substantial source of morbidity. For instance, in the case of burnt skin tissue, self-healing is in fact a large and challenging barrier to tissue regeneration. Squalene is a bioactive triterpene that occurs naturally and plays a key role in the process of making sterols. The most well-known source of squalene is shark liver oil. Vegetable oils may contain squalene in a range of concentrations. They have been extracted using a variety of techniques, including supercritical carbon dioxide, microwave, ultrasonic, cold press, and traditional Soxhlet extractions. In vitro and in animal models, these substances have been demonstrated to have anticancer, antioxidant, drug carrier, detoxifier, skin moisturising, and emollient effects.