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Maximum people worldwide experience acidity occasionally. The prevalence of hyperacidity is increasing day by day due to multiple factors like, frequent use of Nonsteroidal anti-inflammatory drugs, by H-pylori infection, life style and daily habits of the people, which include eating high amount of meal and lying down after taking meal, food with high fat amount, types of food that can tend to increases acidity in stomach, family history of GERD, drinks like alcohol, smoking, high body mass index (BMI), less physical activity and age (Matsuura et al., 2013; Ter et al., 1998). The continuous experience of acidity symptoms on a regular basis can produce countable effects on quality of life (Dean et al., 2004; Tack et al., 2012; Pilotto et al., 2016; Maekawa et al., 1998). Additionally Gastric hyperacidity eventually may precipitates into Gastroesophageal reflux disease (GERD) (Craven et al., 2018, Johnson et al., 2004). It is a state of gastric hyperacidity where acid content from the stomach reverse back into the esophagus (Ness-Jensen et al., 2012). If GERD is left untreated, it may lead to life-threatening complications, like peptic ulcer, perforation and bleeding of GIT due to ulcer, Failure of esophageal peristalsis (Achem. Et al, 2003) and laryngopharyngeal carcinoma (Jarosz et al., 2014;). The worldwide prevalence of GERD is about 8.8–25.9% in Europe, 18.1–27.8% in North America, 11.6% in Australia, 8.7–33.1% in the Middle East, 2.5–7.8% in East Asia and 23.0% in South America (El-Serag et al., 2014, Mahadeva et al., 2005; Eusebi et al., 2018). Simultaneously, there is also an increase in economic burden of health care system by rise in prevalence of the GERD and other complications (Becher et al., 2011). In most of such cases of gastric hyperacidity, people are not consulting with health care provider, but there are the cases were people are needed to be hospitalized as well as have to go though invasive surgeries when there are complications due to high GIT (Gastrointestinal system) damage (Thukkani et al., 2010; Sonnenberg et al., 1994). Despite of high research and discovery of different class of new drugs till date in this area, there is no promising agent to deal with the chronic hyper gastric acidity, GERD and Gastric ulcer (Vaezi et al., 2017; Fass et al., 2001). The drugs like antacids and other present antisecretory agents can deal with Hyperacidity and neutralize it or decrease the acid secretion. But even though people are getting temporary relief from the symptoms on taking available drugs and relapse of acidity is frequently seen in many cases. Therefore the permanent solution is needed to be searched to address this situation. In addition, many patients are required to take medicines for longer time to deal with gastric disturbance generated by treatment of different types of cancers or while undergoing long term treatment of some infections like Tuberculosis. So, drug induced Hyperacidity is also the matter of concern.